Allergan The Makers of Botox To Receive EU Approval For Overactive Bladder Control

Dr Nirdosh® | Allergan’s Botox to receive EU Approval for Bladder Control

 

Allergan says that Botox, best-known for its cure for wrinkles, is within the verge of currently being accredited in Europe to assist bladder control. Botox (botulinum toxin form A) has acquired a view through the Irish Medications Board to the therapy of idiopathic overactive bladder (OAB) with signs of urinary incontinence, urgency and frequency in older people that have an inadequate response to, or are intolerant of, anticholinergic medicines.

This is all based on Allergan’s Clinical Test Results on Bladder Control

The good view is based on the final results of two Section III trials involving, one hundred subjects. In these reports, sufferers who acquired qualified injections of Botox to the bladder muscle mass experienced an important and clinically relevant reaction to treatment when compared with the infamous placebo. Allergan pointed out that idiopathic OAB is “surprisingly prevalent in Europe”, with scientific tests indicating that as many as 16.6% of your inhabitants might arrive at a surgery with the problem. Of those, as many as 36% associate urinary incontinence connected with urgency

What Does Allergan’s President say about Bladder Control?

Douglas Ingram, president of Allergan in Europe, Africa plus the Middle East, claimed that getting powerful management over their bladder without having the dread of leakage just after only one treatment can be a major factor towards improving quality of everyday living for patients.
At the same time as remaining as a wrinkle smoother injectable, Botox is additionally made use of for a number of other indications, together with long-term migraine, certain facial spasms, cervical dystonia, increased sweating from the armpits plus the remedy of post-stroke spasticity in the hand and wrist.

Book your Free consultation call Dr Nirdosh | The Botox Doctor London on 020 7467 1524

 

Advertisements

Skin Ageing | The Science

How the skin ages

SKIN AGEING by Dr Nirdosh

 

Wrinkles are visible as deep folds, ridges, creases and even fine lines in the skin which typically make their appearance as we age. We all get to experience what deep wrinkles can look like on our skin when we spend a long time submerged in water. First stage wrinkles commonly appear on the face as a result of facial expressions. Other factors that can cause facial wrinkles and skin aging include lifestyle traits such as smoking, sun damage, poor nutrition and lack of sleep, among others.

Skin is composed of three layers.

1.      The epidermis which is the external layer of the skin. It acts as a wall against the outside world.

2.      The second layer is the dermis. It houses the connective tissues, which are the structural basics of our skin. There are different kinds of connective tissue and they each have different functions. For instance, collagen is what gives strength to the skin while elastin keeps the skin elastic. There is one important structure found between the epidermis and the dermis, the dermal-epidermal junction.

3.      The third layer is the Subcutaneous Tissue. This bottom layer contains fat cells which are responsible for insulating the body and can give skin a full or plump look.

Main contributing factors to wrinkles and skin ageing:

 

Chronological Aging:

As we get older, the epidermal cells in skin gradually becomes less sticky and thinner. The thinner cells, in turn, give the skin a thinner appearance while the cells’ reduced stickiness lessens the efficacy of the barrier function which enables the skin to lose moisture, causing dryness. Ageing also causes the skin to produce less collagen and the elastin fibres start to wear down. The dermal-epidermal junction’s rete-ridges also flatten out which results in a more brittle skin.  At the bottom layer, the fat cells also become smaller which makes wrinkles and sagging more prominent. This is how the layers work in unison and the skin composition are affected by ageing.

Hormone Effects

Hormones I believe are the biggest cause of ageing and I have unlocked the ageing code and explained this in my book Dr Nirdosh’ Anti Ageing Secrets. Research suggests that the hormonal changes due to reduced estrogen production or menopause can also cause changes in the skin such as wrinkles.

Aging Effects of the Sun

Being exposed to ultraviolet light from the sun can be attributed to 90% of skin ageing clearly showing signs of premature ageing. The majority of these photo aging effects can start by the time at 20 years old.

Free Radicals:

Free radicals refer to the unstable molecules of oxygen which contain just one electron rather than the normal two. Free radicals can result in wrinkles because it activates metalloproteinase’s which destroys collagen. A number of factors can trigger this process such as being exposed to UV radiation from the sun, smoking and air pollution. This process occurring will instigate cross linkage formation which is the birth of a wrinkle.

Muscle Use:

Much-repeated facial expressions are known to cause the skin to lose elasticity, resulting in wrinkles. Frown lines and crows feet form due to the repeated contraction of the muscles in the eye area.

Gravity:

Gravity makes the sagging of the skin more prominent which in turn causes baggy eyelids and jowls.

Genes:

Looking at your mother will give you a good indication of how the ageing principle of ‘mom-warping’ is not a new phenomenon but rather a fact you must learn to accept. This does not mean you cannot take prior action to change your youth destiny, but quite the opposite. If mom has not aged gracefully – it’s time to take action early to prevent you from following the same facial map.

Contact Dr Nirdosh London now to arrange your FREE CONSULTATION with Dr Nirdosh at Harley Street on 020 7467 1524.

Why You Need A Facelift

you need a facelift copy

Why You Need A Facelift

Growing old is a fear for many. A massive part of that fear isn’t medical but rather aesthetic. Losing your youthful looks can cause anxieties. A great number of women consider a facelift as soon as see tell-tale aging signs. They want their physical appearance to match how they feel inside – youthful, vibrant and full of energy. If you find yourself in this predicament, worrying constantly about your face and how it is ageing, you may need a facelift. It may not be realistic to expect that a facelift can make you look twenty again; however it can certainly help you keep up a glowing youthful appearance for many years.

The main causes of why you need a facelift!

If you want to know the causes of why you need a facelift, you should start by examining your skin. You may need a facelift if your skin is sagging and wrinkles have appeared on your face, especially the lower portion. If this is you and you have made the decision to want a facelift, plan early ahead, because a good facelift candidate is someone who has ample bone structure and whose skin is still elastic.

Ageing is still the primary reason why you need a facelift. As a result of the aging process, you may find that the skin on your face has sagged to the neck resulting in an unpleasant appearance. By obtaining a facelift, you will be able to restore the tightness of your neck skin and at the same time, you can address any issues with muscle and fat underneath the skin. The facelift brings back the firmness of the entire face, resulting in a younger-looking appearance. An unsightly jaw may also be a reason why you need a facelift. A firm jaw contributes significantly to a youthful and healthy appearance. However, the aging process can loosen the skin around the jaw which causes the jaw to seemingly disappear. Consequently, you end up looking tired, old and in poor shape.

 

How about a mid face-lift?

Patients can also go for a mid facelift which diminishes the appearance of wrinkles close to the mouth and eyes. A mid-facelift doesn’t treat the neck and jowl area. It’s less invasive compared to a full facelift and has a shorter recovery period.

What to do next on your facelift journey?

If you want to know more about why you may need a facelift, schedule an appointment with the Dr Nirdosh Clinic London. During your consultation, leading Harley Street cosmetic doctor Dr Nirdosh will first ascertain your goals and anticipated results for the eventual facelift. What parts of your physical appearance you desire to alter and your actual reasons. Dr Nirdosh will consider all of the information including your medical history and inspect your face before discussing your different options. Dr Nirdosh will then advise accordingly on whether you would be a good candidate for a facelift or rather a less invasive procedure including a full non-cosmetic facelift, which could possibly give you quicker and better results.

Paul O Grady blames wrinkles for the demise of Lily Savage

Paul O Grady reveals wrinkles are the reason his alter ego Lily Savage will not return.

“I’m 57, I feel I’m 207. I look in the mirror and I think, ‘That’s not a wrinkle, it’s a gutter across my face!. That’s the exact quote from Paul O’ Grady as he  announced there will be no more Lily Savage on the small screen.

The presenter, who has released the latest volume of his memoirs, Still Standing, is dusting off the heels to bring Lily back in panto this Christmas, as Widow Twankey in Aladdin at the O2. But he said that this will be the last time.

He also blames technology.  High definition will show up all the wrinkles. Lily Savage will never do telly again. Not with HD,” he admitted.

FRENCH WOMEN MORE LIKELY TO GET LIP WRINKLES

So Why Do French Women Get Lip Wrinkles?

 

It’s called the ‘FRENCH PUCKER’ and to speak the french language like a true native, you have to close your lips quite tightly to pronounce words and vowels. You can see in the example below of Christine Lagarde.

 

https://i0.wp.com/3.bp.blogspot.com/_Y0pLn9JmlUo/TQsLdCMhK9I/AAAAAAAAQaM/N21B7Nb-owk/s1600/P1060838b.jpg

Christine Lagarde – Europe’s first lady is French and has noticable lip wrinkles

 

The English language in comparison is spoken from the lower jaw whereas French is a language that requires your lips to be puckered quiet frequently.

 

https://i2.wp.com/3.bp.blogspot.com/_Y0pLn9JmlUo/TQsN2AT1nwI/AAAAAAAAQak/tiVNj3QmMuk/s1600/bb.jpg

A picture of Brigitte Bardot clearly exposing her french lip wrinkles.

 

Cosmetic surgery procedures at the Dr Nirdosh Clinic such as Lip Augmentation can correct lip wrinkles and iron out lines to give a wrinkle free area. This is only half the battle. Lifestyle changes must be implemented to prevent further wrinkle formation.  These include

 

1. Stop smoking

Years of puckering up to a cigarette and sucking in the smoke creates premature lip wrinkles.  The obicularis oris muscle around the lips becomes overused and causes wrinkles around the lips.

 

 

2. Be careful with laser treatments around the lip area

Laser around this delicate area can destroy the collagen leaving the lip area with saggy skin and wrinkles.

 

3.  Use UV protection

The suns rays destroy the lips skins elasticity as the skin around the lip area is exceptionally thin and prone to fine lines.

 

4. Stop using a straw to drink

Many women use a straw to avoid make-up disasters and to avoid teeth staining from wine and coffee. This movement is similar to smoking a cigarette. If you do this frequently you need to stop.

 

 

5. Genetics

Take action early if you notice your mother has lip wrinkles. Genetics are a powerful force and there’s every possibility you too will have lip wrinkles at her age. So take action now.

 

 

 

 

 

 

 

 

 

Natural beauty Gwyneth will have cosmetic surgery

So What Has Convinced Gwyneth Paltrow To Go Under The Knife? 

Gwyneth

She is a natural beauty with a calm exposure, one who refrains to be seduced by all the Hollywood razzamatazz. That is until it comes to her face. Gwyneth Paltrow has revelaed that she is not immune to cosmetic surgery and when the fines lines become more visible, she will be happy to find herself sitting in the cosmetic chair.

Gwyneth Paltrow

Gwyneth has not taken this decision likely

Her decision is not one without fear as she knows having movement on her face is paramount in her career as a leading actress but this is something she will have to face nearer the time. Gwyneth – who this week was named the World’s Best Dressed Woman by People magazine – said: ”Everyone is asking me about my thoughts on plastic surgery. Do I look old or something?! I’m not opposed to it but I want to move my face because I’m supposed to convey emotion in my job. But I have wrinkles so I don’t know – I’m not going to say that I’ll never do anything, but I would always want to look like myself.”

Gwyneth Paltrow